Aimee S Payne, MD, PhD

Accepting New Patients
Virtual Visits/Telehealth
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Areas of Expertise / Conditions Treated

  • Blistering Disorders
  • Medical Dermatology

Academic Appointments

  • Professor of Dermatology

Administrative Titles

  • Chair, Department of Dermatology
  • Dermatologist-in-Chief, NewYork-Presbyterian Hospital

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Female

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Virtual Visits/Telehealth

Virtual Visits allow you to connect with your provider from the comfort, convenience, and safety of your own home.

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Phone Appointments

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161 Fort Washington Avenue
New York, NY 10032

Insurance Accepted


  • Aetna Signature Administrators
  • EPO
  • HMO
  • Medicare Managed Care
  • NYP Employee Plan
  • NY Signature
  • POS
  • PPO
  • Student Health


  • EPO
  • Great West (National)
  • HMO
  • Medicare Managed Care
  • POS
  • PPO


  • Medicare Managed Care
  • PPO


  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross/Blue Shield

  • EPO
  • HMO
  • PPO

Fidelis Care

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare


  • Railroad
  • Traditional Medicare


  • Multiplan

Quality Health Management

  • Quality Health Management


  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicare Managed Care
  • Oxford Freedom
  • Oxford HMO
  • Oxford Liberty
  • POS
  • PPO

World Trade Center Health Plan

  • World Trade Center Health Plan

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • BS, 1993 Biology, Stanford University
  • MD, 2001 Washington University School of Medicine
  • PhD, 2001 Molecular And Cellular Biology, Washington University School Of Medicine
  • Internship: 2002 Pennsylvania Hospital
  • Residency: 2005 Hospital of the University of Pennsylvania
  • Fellowship: 2006 University of Pennsylvania

Committees, Societies, Councils

  • 2023-2024: President-Elect of the Society for Investigative Dermatology
  • Served as Chair of the National Institute of Arthritis and Musculoskeletal and Skin Diseases Board of Scientific Counselors
  • Elected Member of the American Society for Clinical Investigation
  • Elected Member of the American Dermatological Association
  • Serves on the Medical Advisory Council of the International Pemphigus and Pemphigoid Foundation

Board Certifications

  • Dermatology

Honors & Awards

  • Co-Founder and Co-Chair of the Scientific Advisory Board of Cabaletta Bio


Researching the pathophysiology and targeted therapy of ?autoantibody-mediated diseases

Research Interests

  • Precision cellular immunotherapies for B cell-mediated diseases
  • Genetic and functional characterization of human anti-desmoglein B cell repertoires

Selected Publications

  1. Oh S, Mao X, Manfredo-Vieira S, Lee J, Patel D, Choi EJ, Alvarado A, Cottman-Thomas E, Maseda D, Tsao PY, Ellebrecht CT, Khella SL, Richman DP, O’Connor KC, Herzberg U, Binder GK, Milone MC, Basu S, Payne AS: Precision targeting of autoantigen-specific B-cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T-cells. Nature Biotechnol in press, 2023.
  2. Tovanabutra N, Bax CE, Feng R, Kushner CJ, Payne AS: Temporal outcomes after rituximab therapy for pemphigus. J. Invest. Dermatol. 142(4): 1058-1064, 2022 Notes: doi:10.1016/j.jid.2021.09.013.
  3. Lee J, Lundgren DK, Mao X, Manfredo-Vieira S, Nunez-Cruz S, Williams EF, Assenmacher CA, Radaelli E, Oh S, Wang B, Ellebrecht CT, Fraietta JA, Milone MC, Payne AS: Antigen specific B-cell depletion for precision therapy of mucosal pemphigus vulgaris. J Clin Invest 130(12): 6317-6324, 2020 Notes: doi:10.1172/JCI13841.
  4. Maehara T, Kaneko N, Perugino CA, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Murphy SJ, Ghebremichael M, Fox DA, Payne AS, Lafyatis R, Stone JH, Khanna D, Pillai S: Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis. J Clin Invest 130(5): 2451-2464, Jan 2020 Notes:
  5. Kushner CJ, Wang S, Tovanabutra N, Tsai DE, Werth VP, Payne AS: Factors associated with complete remission after rituximab therapy for pemphigus. JAMA Dermatol 155(12): 1404-09, 2019 Notes: doi:10.1001/jamadermatol.2019.3236.
  6. Cho A, Caldara AL, Ran NA, Menne Z, Kauffman RC, Affer M, Llovet A, Norwood C, Scanlan A, Mantus G, Bradley B, Zimmer S, Schmidt T, Hertl M, Payne AS, Feldman R, Kowalczyk AP, Wrammert J : Single-cell analysis suggests that ongoing affinity maturation drives the emergence of pemphigus vulgaris autoimmune disease. Cell Rep 28(4): 909-922, Jul 23 2019.
  7. Ellebrecht CT, Mukherjee EM, Zheng Q, Choi EJ, Reddy SG, Mao X, Payne AS: Autoreactive IgG and IgA B cells evolve through distinct subclass switch pathways in the autoimmune disease pemphigus vulgaris. Cell Rep 24(9): 2370-2380, Aug 28 2018.
  8. Mao X, Cho MJ, Ellebrecht CT, Mukherjee EM, Payne AS: Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes. JCI Insight 2(9): e92253, May 4 2017.
  9. Ellebrecht CT, Bhoj VG, Nace A, Choi EJ, Mao X, Cho MJ, Di Zenzo G, Lanzavecchia A, Seykora JT, Cotsarelis G, Milone MC, Payne AS: Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease. Science 353(6295): 179-184, Jul 8 2016.
  10. Cho MJ, Lo ASY, Mao X, Nagler AR, Ellebrecht CT, Mukherjee EM, Hammers CM, Choi EJ, Sharma PM, Uduman M, Li H, Rux AH, Farber SA, Rubin CB, Kleinstein SH, Sachais BS, Posner MR, Cavacini LA, Payne AS: Shared VH1-46 gene usage by pemphigus vulgaris autoantibodies indicates common humoral immune responses among patients. Nature Commun 5: 4167, Jun 19 2014.